Monobenzone Is Not For Treating Freckles, Café-au-lait Spots, Sun Damage, Melanoma, Jaundice, Or Other Pigmentation Disorders Not Caused By Vitiligo. Monobenzone May Also Be Used For Purposes Not Listed In This Medication Guide.
BRAND NAME(S): Benoquin. USES: Monobenzone is used to treat the uneven appearance of the skin due to a loss of skin color (vitiligo). It works by permanently removing color from normal skin located around the skin with vitiligo.
Benoquin Cream 20% contains a potent depigmenting agent and is not a cosmetic skin bleach. Use of Benoquin Cream 20% is contraindicated in any conditions other than disseminated vitiligo. Use only for final depigmentation in extensive vitiligo.
Benoquin is a topical prescription drug approved by the U.S. Food and Drug Administration (FDA) for removing pigment in people with vitiligo that covers more than 50 percent of their body. 1,2 The skin-bleaching effects of Benoquin are permanent and irreversible.
It achieves its effects by inducing the necrotic death of melanocytes. Topical all-trans-retinoic acid (RA), a vitamin A derivative, causes mild depigmentation and, when combined with MBEH, has synergistic effects, yielding depigmentation quickly.
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